- First of all, editing isn't typically done in SpeedGrade or After Effects, it's done in Premiere Pro.
- Typically, you color grade after the editing is done in Premiere Pro.
- You can color grade within Premiere Pro with its native color correction tools.
- If the tools in Premiere Pro don't give you the results you need, you can export your sequence (or an EDL) to bring into SpeedGrade.
- I use After Effects for titling, motion graphics and visual effects. Most of the time, I create these things after I finish editing in Premiere Pro.
Hope that helps.